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The clinical relevance of increasing our knowledge about epigenetic disturbances in oligodendrocytes and astrocytes stems from the demonstration of significant epigenetic anomalies in demyelinating disorders, and the possibility of reversing them with experimental treatments targeted to epigenetic alterations (Li and Yao, 2012
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Every single cell in your bodyfrom the neurons in your brain to the hepatocytes in your liveris encased in a protective barrier known as the cellular membrane
Because SLC7A11 regulates GSH synthesis (through intracellular cystine availability) and 15LO1 decreases intracellular GSH, a high SLC7A11 to 15LO1 protein ratio likely supports high/normal intracellular GSH
